2-Pyridinecarboxamide, 5-[4-[(7-ethyl-5,6-dihydro-6-oxo-1,5-naphthyridin-3-yl)methyl]-1-piperazinyl]-N-methyl-
AZD5305
CAS: 2589531-76-8
Molecular Formula: C22H26N6O2
2-Pyridinecarboxamide, 5-[4-[(7-ethyl-5,6-dihydro-6-oxo-1,5-naphthyridin-3-yl)methyl]-1-piperazinyl]-N-methyl- - Names and Identifiers
2-Pyridinecarboxamide, 5-[4-[(7-ethyl-5,6-dihydro-6-oxo-1,5-naphthyridin-3-yl)methyl]-1-piperazinyl]-N-methyl- - Physico-chemical Properties
| Molecular Formula | C22H26N6O2 |
| Molar Mass | 406.48 |
| Solubility | Soluble in DMSO |
| Storage Condition | -20℃ |
| Use | AZD5305 is a potent, selective and oral active PARP inhibitor. AZD5305 is a highly potent inhibitor of PARP1, with significant PARP1-DNA trapping activity, no PARP2-activity, nor binding activity to any other members of the PARP family. AZD5305 has excellent secondary pharmacology and physicochemical properties as well as high oral bioavailability in preclinical species. |
| Target | PARP |
2-Pyridinecarboxamide, 5-[4-[(7-ethyl-5,6-dihydro-6-oxo-1,5-naphthyridin-3-yl)methyl]-1-piperazinyl]-N-methyl- - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.46 ml | 12.3 ml | 24.601 ml |
| 5 mM | 0.492 ml | 2.46 ml | 4.92 ml |
| 10 mM | 0.246 ml | 1.23 ml | 2.46 ml |
| 5 mM | 0.049 ml | 0.246 ml | 0.492 ml |
Last Update：2024-01-02 23:10:35
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Spot supply
Product Name: AZD5305 Visit Supplier Webpage Request for quotationCAS: 2589531-76-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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